Máspero JF, Parisi CA, De Gennaro M, Benhabib O, Lampert M
[Chronic autoimmune urticaria: treatment with omalizumab] [English Abstract, Journal Article]
Arch Argent Pediatr 2009 Oct; 107(5):452-6.
We report the case of a child with diagnosis of chronic urticaria/angioedema and its evolution upon omalizumab treatment.
CASE REPORT: Our patient is a 12-years-old female who suffered for 14 months severe chronic urticaria/angioedema. She had a poor response to the highest doses of combined therapy with 3 antihistamines, steroids and anti-leukotrienes and great impairment of her quality of life. An autologous serum skin test was positive until 1:100 dilutions, leading to the diagnosis of chronic autoimmune urticaria. Due to the lack of response to treatment, therapy with omalizumab was administered. A notable reduction in symptoms toward the third dose was observed. After 12 months of this treatment, the patient is asymptomatic and has a negative autologous serum test.
CONCLUSION: Omalizumab could be a therapeutic option for patients with autoimmune urticaria unresponsive to other treatments.
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